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164 CE

This year falls in the Classical antiquity (c. 500 BCE–500 CE). Large empires rule much of Eurasia, among them Persia, the Maurya and Gupta states of India, Han China and Rome. Classical Greece, the spread of Buddhism and the rise of Christianity belong to this era, which ends as the western Roman Empire falls in the fifth century CE.

Within fifteen years

Philosopher · Classical antiquity · EgyptSextus Empiricusc. 160–c. 210Greek physician and skeptic who lived at Alexandria and Athens around 160 to 210. His Outlines of Pyrrhonism is the fullest surviving account of ancient skepticism. His birthplace is unknown.

Philosopher · Classical antiquity · IndiaNagarjunac. 150–c. 250Indian Buddhist thinker, founder of the Madhyamaka middle way school, who argued that all things are empty of inherent existence. His Mulamadhyamakakarika is the central text of Mahayana philosophy. He lived about 150 to 250.